We’ve all heard about the dangers of high cholesterol.
Lifestyle is a considerable determinant of our cholesterol levels.
But did you know that our genes also play a significant role?
And while rare, HoFH is worth knowing about.
What is homozygous familial hypercholesterolemia (HoFH)?
This genetic disorder causes cholesterol to be more than four times the typical level.
While this is serious, many patients aren’t diagnosed or only find out about it later in life.
Based on population estimates, approximately 1,300 people in the U.S. have HoFH.
Only 5% of rare diseases like HoFH actually have an FDA-approved treatment.
Startled by the results, Scott quickly underwent bypass surgeryjust days after his gym incident.
Despite being a fit 43-year-old dad, Scott was diagnosed with HoFH.
Because of that, a nurse suggested that he have his kids' cholesterol levels checked as a precaution.
Scott spent the next six years devoting his life to helping navigate his daughter’s condition.
Chloe was prescribed statins and other cholesterol-lowering medications.
Despite trying different treatments, Chloe’s cholesterol remained abnormally high.
While the treatment did improve her cholesterol, she found it difficult to maintain this routine.
She was behind in school from doctor’s appointments and days spent receiving apheresis treatment.
Scott noticed that she was struggling.
He followed the clinical trials closely until the drug was approved asEVKEEZA(evinacumab-dgnb) in February 2021. yo see additional important safety information below and clickherefor full prescribing information.
“Today, I’m grateful for that ‘worst day of my life,'” Scott says.
How does EVKEEZA work?
So, how does this treatment work?
EVKEEZA was invented by Regeneron, using the company’s VelocImmunetechnology.
And, just like Scott and Chloe, people can find a way to help manage their rare disease.
It is not known if EVKEEZA is safe and effective in people with other causes of high cholesterol.
The effect of EVKEEZA on heart problems such as heart attacks, stroke, or death is not known.
It is not known if EVKEEZA is safe and effective in children with HoFH under 5 years of age.
Tell your health care provider if you have any side effect that bothers you or does not go away.
These are not all the possible side effects of EVKEEZA.
Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088.
just see fullprescribing information, includingpatient information.
